fibre7orange
Messages : 612 Date d'inscription : 22/01/2013
| Sujet: Different approaches attempted to decipher the role of desaturation Mer 7 Fév - 7:14 | |
| However, a recent study claims that membrane protein stability does not depend on the lipid composition of the membrane and arguments against lipid saturation per se as a regulator of thermotolerance were raised. The present study supports the possibility that both lipid saturation/rigidification CX-4945 PKC inhibitor and point mutations that modify the protein structure at the transition state may be required for controlling the activation energy for the ratedetermining electron transfer and for inducing thermotolerance to the PSIIRC. Namely, as the growth temperature is increased to 43uC, DH{ and DS{ for the AC mutant should be changed for maintaining ket at 3000–3500 s21. To that end the DBI value decreases to counteract CYT387 JAK inhibitor the increased fluidity of the membrane at elevated temperatures. At the same time our study suggests that in addition to the enhanced functional stabilization of the PSIIRC complex, there is a need to attenuate the impairment of the D1 repair machinery at elevated temperature, possibly by providing more CO2 as a sink for the accumulation of redox equivalents. | |
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