Blood and serum samples were collected for measurements of serum calcium

It also relieves brain injury by reducing neuronal damages in cerebral ischemia. BIBW2992 EGFR/HER2 inhibitor Sal B can improve cellular hypoxia-ischemia by expanding micro-arteries, improving microcirculation and increasing the blood flow velocity. Its beneficial effects on blood vessel dilation and protection are believed to be mediated by blocking calcium channels and angiotensin-converting enzyme. Moreover, Salvia miltiorrhiza Bunge and its aqueous extract can increase the activity of superoxide dismutase, scavenge reactive oxygen species and therefore reduce the damage of ROS to the vascular endothelium. Thus, Sal B functions as a vasodilator, maintains red blood cell deformability and increases the function of the hematopoietic system. Recently, our in vitro studies have demonstrated that Sal NVP-BKM120 PI3K inhibitor A can inhibit glucocorticoid– induced bone marrow stromal cells adipogenesis, promote osteoblast differentiation, bone matrix formation and bone mineralization.